Patients randomized to MB/U-MDT group, receiving 6 MDT doses, were closely monitored and evaluated twelve times as the MB/R-MDT patients that received 12 MDT doses. Therefore, the 13 th blood collection corresponds to 210 days after the last MDT dose for MB/U-MDT patients and 30 days for MB/R-MDT patients. Table 1 Baseline characteristics of 753 leprosy patients, according to treatment groups. Considering the other red blood cell results, it was observed that only MCHC did not show statistically significant parameters when the mean average between the different groups during treatment was compared. Although more evident in the PB/U-MDT group, MCV and MCH presented high basal mean increase after the first dose in all groups and remained high during treatment. In MB/U-MDT group, a decrease was observed only after completion of treatment, almost reaching baseline levels; the MB/R-MDT group remained high during all treatment. The main AE presented in this paper is part of the prospective Brazilian Clinical Trial for Uniform Multidrug Therapy of Leprosy (U-MDT/CT-BR).
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