Bónus 200 bonus 1xbet Grátis Disponível. Hsd3b1 is responsible for the oxidation and isomerization of Δ5-3β-hydroxysteroid precursors in order to form Δ4-3-ketosteroid (Nakamoto et al., 2012). Hsd11b2 catalyzes the conversion of cortisol to cortisone (Fuller et al., 2012), and also plays a crucial role in the conversion of 11β-OH-androstenedione to 11-ketotestosterone (11-KT) (Tokarz et al., 2015), which affects the production of the most important androgen in teleost fish. Furthermore Hsd17b1 converts inactive estrone to active estradiol (Mindnich et al., 2004), Hsd17b3 is an essential enzyme for the synthesis of 11-KT (Mindnich et al., 2005) and Hsd20b2 converts 17alpha-hydroxyprogesterone to 17alpha,20beta-DP, which has been identified as the maturation-inducing hormone of several teleosts (Senthilkumaran et al., 2002). Genome-Wide Identification of β -hsd Genes. Gene Expression Profiling by Quantitative Real-Time PCR (qRT-PCR) The exon-intron structure of the grouper β -hsd genes was further characterized, and showed that the number of introns in each β -hsd gene varied from 2–16 (Figure 2B). Hsd3b1 was the gene with the lowest number of introns, containing only two, while hsd17b4 had the greatest amount at 16. In addition, a phylogenetic tree was constructed using the grouper β-HSD protein sequences to determine whether the exon-intron structure is consistent with the phylogenetic tree (Figure 2A).
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18+ In the 1950s, the team was led by Avtandil Gogoberidze who spent 17 years with Dinamo. He still holds the record for games played and goals scored for Dinamo, with 341 matches and 127 goals. In the same period, the following players starred for Dinamo: G. Antadze, Vladimer Marghania, N. Dziapshipa, M. Minaev, A. Zazroev, V. Eloshvili, and Avtandil Chkuaseli. A prominent place in Dinamo history belongs to Andro Jordania, a coach who is considered as one most important figures in the club's history. His period in charge was seen as ”the Renaissance” of Dinamo's traditions, which laid the ground for the major successes connected with his name. The club's Digomi practice ground is named after him. Disco bingo.Países do Reino Unido. Cada um possui um parlamento próprio, bandeira e chefe de governo.
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Lokomotiv 1929 (Bulgarian: Локомотив 1929 ) is a Bulgarian professional association football club based in Sofia, which currently plays in the First League, the top tier of Bulgarian football. Contents. PFC Lokomotiv Sofia in 2022. Winners (2): 1961, 1963. 1960-1990: Continued domestic and European success Edit. In 1980 Lokomotiv reached a quarter final in the UEFA Cup where they faced VfB Stuttgart, eliminating before that Ferencváros, AS Monaco and Dynamo Kyiv. Against Stuttgart the team lost with 0–1 in Sofia and with 1–3 in Germany. The new era for Lokomotiv Sofia came in 1994 with the new president Nikolay Gigov. The football club's status was turned professional. For merely one year (1994–95), from a team struggling not to lose its place in the professional league, Lokomotiv won the silver medals in the Championship and the State Cup.
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